You should be fine as long you gracefully shut down the node before unplugging it. You can do that by the dashboard or SSH.
Dashboard: Login, bottom left Settings > Shutdown
SSH: sudo shutdown -h now
When doing the SSH route, wait at least 2-5 minutes or until there is no disk activity from the SSD/HDD by looking at the indicator light.
I have the exact same case for my Adguard DNS server and running WCG/Rosetta@Home and it has been chugging along without any issues. Just that you might need to clean out the case every other week with a spray of canned air. We don’t want dust bunnies clogging up the fan!